BioProduct : Immunology : Immunohistochemistry Reagents : HER2 : ErbB2
Previous  Next
Visit the product
Product Name HER2 / ErbB2
Product PageVisit the Product
Product Description HER2 / ErbB2 is one of the four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases (1). The kinase activity of ErbB2 can be activated without ligand if it is overexpressed, and by association with other ErbB proteins (2). Overexpression of ErbB2 is detected in almost 40% of human breast cancers (3). Binding of c-Cbl ubiquitin ligase to Tyr1112 of ErbB2 leads to poly-ubiquitination of ErbB2 and enhances its degradation (4). ErbB2 is one of the major targets for the treatment of breast cancer and other carcinomas.
Product Manual Read Product Manual
Price $250.00
Product Review 0
Vendor Information
863 Mitten Road, Suite 103
CA 94010

Phone: (877) 772-2622
Fax: (650) 583-6680