BioProduct : Immunology : ELISA : Canine Vascular Endothelial cell Growth Factor,VEGF ELISA KIT
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Product Name Canine Vascular Endothelial cell Growth Factor,VEGF ELISA KIT
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Product Description Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) or vasculotropin , is a homodimeric 34 -42 kDa, heparin-binding glycoprotein with potent angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. The amino acid sequence of VEGF exhibits primary structural, as well as limited amino acid sequence, homology with that of the A and B chains of PDGF. VEGF is expressed by numerous rodent and tumor cells, including lung adenocarcinoma, bladder carcinoma, fibrosarcoma, HL60 promyelocytic leukemia, GS-9L glioma, and U937 lymphoma cells. In normal tissues, VEGF expression has been found in activated macrophages, keratinocytes, renal glomerular visceral epithelium and mesangial cells, hepatocytes, smooth muscle cells , Leydig cells ,embryonic fibroblasts and bronchial and choroid plexus epithelium. The expression of VEGF is upregulated by phorbol ester, TGF-a and in hypoxia. In the conditioned media of human choriocarcinoma cells (JAR and JE-3), the occurrence of VEGF/PlGF heterodimers has also been observed.
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Price $900
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