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BioProduct : Immunology : Immunohistochemistry Reagents : Bcl-2
| Product Name | Bcl-2 |
| Product Page | Visit the Product |
| Product Description | The Bcl-2 family of proteins regulate apoptosis by controlling mitochondrial permeability and release of cytochrome c. Bcl-2 is an anti-apoptotic protein that resides in the outer mitochondrial wall and inhibits release of cytochrome c (1). Over-expression of Bcl-2 has been shown to promote cell survival by suppressing apoptosis. It has been documented that bcl-2 becomes deregulated in tumor cells as a result of translocation into the immunoglobulin heavy-chain locus and is therefore activated in B cell malignancies (2). It has also been shown that post-translational modification of Bcl-2, phosphorylation at serine 70, may be required to render its full and/or enhanced anti-apoptotic effect (3, 4). |
| Product Manual | Read Product Manual |
| Price | $250.00 |
| Specification | 100ul |
| Product Review | 0
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| Vendor Information |  Epitomics https://www.epitomics.com/products/index.php 863 Mitten Road, Suite 103 Burlingame CA 94010 USA Phone: (877) 772-2622 Fax: (650) 583-6680 E-Mail: Rabmabs@epitomics.com |