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site-directed mutagenesis of lysine - (Jan/30/2007 )

Hi to all best people!

I want to do a site-directed mutagenesis of lysine... anyone can tell me the best aminoacid substitute? and why?

I think that this lysine it's important for intramolecular interactions... please if you can give also reference! smile.gif

Thanks in advance.


Anyone can help me?