TRIzol v. TRI reagent - (Mar/06/2010 )

TRI reagent from sigma versus TRIzol from invitrogen? is there a difference? could i substitute TRI reagent in this protocol: http://keck.med.yale.edu/microarrays/proto...tion_092107.pdf

thank you!

I don't see why not, but it could also depend on your downstream app. For our project, it made no difference.

Hm, I assumed it's the same "chemistry"/solution just from a different supplier. I mixed TRI reagent with TriZol from our neighboring lab when I ran out of TRI reagent... for expression profiling. It worked for me.